Effect Runes in Diablo 4 are one of the two kind of Runes that can be found on the game. Effect Runes provide powerful effects while active, but require the conditions on a Condition Rune to be met. Combining similar Effect Runes and Condition Runes can help the player to increase the effectiveness of a playstyle or to reinforce a weak area of his build.

 

 

Effect Runes in Diablo 4

 

Name/Icon

Effect

dol_effect_rune_diablo_4_wiki_guide
Dol
normal_2_modifier_icon_diablo_4_wiki_guide_20pxWhen active, gain 50% critical strike chance for 7 seconds
sol_effect_rune_diablo_4_wiki_guide
Sol
normal_2_modifier_icon_diablo_4_wiki_guide_20px When active, gain a random shrine effect for 7 seconds
ist_effect_rune_diablo_4_wiki_guide
Ist
normal_2_modifier_icon_diablo_4_wiki_guide_20px When active, your next thorns hit deals 30% more
thul_effect_rune_diablo_4_wiki_guide
Thul
normal_2_modifier_icon_diablo_4_wiki_guide_20pxWhen active, gain 500 damage barrier

 

 




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