Sorceress Major Destruction Skills in Diablo 4 are assigned to the Right Mouse button and are a more powerful compared to Minor Destruction Skills, they consume Mana when cast. There are 6 Sorceress Major Destruction Skills and these are: Charged Bolts, Fireball, Ice Shards, Incinerate, Chain Lightning, Frozen Orb. Below you can see what each Sorceress Major Destruction Skills do and their effect on enemies:
Sorceress Major Destruction Skills
Charged Bolts
Mana Cost: 18
Release 6 bolts of lightning that course along the ground in an erratic pattern, dealing X damage each.
Deals Lightning Damage
Fireball
Mana Cost: 30
Hurl a ball of fire that explodes on contact, dealing X damage to nearby enemies.
Deals Fire Damage
Ice Shards
Mana Cost: 18
Launch 5 shards that deal X damage each.
Deals X% more to Frozen enemies.
Deals Cold Damage
Incinerate
Mana Cost: 20 per second
Channel a beam of fire, burning enemies for X damage. Damage increases by X per second, up to X.
Deals Fire Damage
Chain Lightning
Mana Cost: 35
Unleash a bolt of lightning, dealing X damage and jumping to X nearby targets.
Deals Lightning Damage
Frozen Orb
Mana Cost: 40
Unleash an orb that Chills and expels piercing shards for a total of X damage, and then explodes into Frost Bolts.
Deals Cold Damage